Literature

Co-promoter:

Esther Creemers: 

o         Wound healing after myocardial infarction. Focus on matrix metalloproteinases

           and the plasminogen system 

o        16 juni 2000

o        Co-promotor: Dr. Ir. J.P.M. Cleutjens

o        Promotor: Prof. Dr. M.J.A.P. Daemen

Cherida Dhore:

o        Atherosclerotic calcification.

o        3 juni 2005

o        Co-promotor: Dr. Ir. J.P.M. Cleutjens

o        Promotor: Prof. Dr. M.J.A.P. Daemen

143

Ganizada, B. H., Reesink, K. D., Parikh, S., Ramaekers, M. J. F. G., Akbulut, A. C., Saraber, P. J. M. H., Debeij, G. P., Mumc-Taa Student Team, Jaminon, A. M., Natour, E., Lorusso, R., Wildberger, J. E., Mees, B., Schurink, G. W., Jacobs, M. J., Cleutjens, J., Krapels, I., Gombert, A., Maessen, J. G., Accord, R., … Bidar, E. (2023). The Maastricht Acquisition Platform for Studying Mechanisms of Cell-Matrix Crosstalk (MAPEX): An Interdisciplinary and Systems Approach towards Understanding Thoracic Aortic Disease.  Biomedicines, 11(8), 2095. https://doi.org/10.3390/biomedicines11082095 

142

van der Weijden, J., De Hoogt, P. A., Leufkens, M. M. E., Keijbeck, A. A., van Goor, H., van den Heuvel, M. C., Cleutjens, J. P. M., Moers, C., Snoeijs, M. G., Navis, G. J., van Londen, M., Nolte, I. M., Berger, S. P., De Borst, M. H., & Peutz-Kootstra, C. J. (2023). The relationship of peritubular capillary density with glomerular volume and kidney function in living kidney donors. Journal of nephrology, 36(7), 2111–2124. https://doi.org/10.1007/s40620-023-01734-5

141

Keijbeck, A., Raaijmaakers, A., Hillen, L., Gelens, M., van Kuijk, S., Cleutjens, J.P.M., Peutz-Kootstra, C. and Christiaans, M. (2023): 82(5):713-721, Visual interstitial fibrosis assessment as continuous variable in protocol renal transplant biopsies. Histopathology. https://doi.org/10.1111/his.14857  

 140

Kuiper, S.Z. , van Tol,  R.R., Lataster, A., Cleutjens, J.P.M., Melenhorst, J., van Dijk, P., van Kuijk, S.M.J., Breukink, S.O. (2022). A Morphometric Analysis of Pathological Alterations in Hemorrhoidal Disease Versus Normal Controls: A Controlled Trial. Journal of Coloproctology 2022; 42(02): 140-145 (DOI: 10.1055/s-0041-1742257)

139

Moshi, J.M. , Ummelen, M., Broers, J.L.V., Smedts, F., Van de Vijver, K.K., Cleutjens, J.P.M., Litjens, R.J.N.T.M., Ramaekers, F.C.S., Hopman A.H.N. (2022): 158(6):545-559. SOX2 expression in the pathogenesis of premalignant lesions of the uterine cervix: its histo-topographical distribution distinguishes between low- and high-grade CIN. Histochem Cell Biol 

 138

Widowski, H., Reynaert, N. L., Ophelders, D., Hutten, M. C., Nikkels, P. G. J., Severens-Rijvers, C. A. H., Cleutjens, J. P. M., Kemp, M. W., Newnham, J. P., Saito, M., Usuda, H., Payne, M. S., Jobe, A. H., Kramer, B. W., Delhaas, T., & Wolfs, T. (2021). Sequential Exposure to Antenatal Microbial Triggers Attenuates Alveolar Growth and Pulmonary Vascular Development and Impacts Pulmonary Epithelial Stem/Progenitor Cells. Front Med (Lausanne), 8, 614239. doi:10.3389/fmed.2021.614239

137

van Gorp, C., de Lange, I. H., Massy, K. R. I., Kessels, L., Jobe, A. H., Cleutjens, J. P. M., Kemp, M. W., Saito, M., Usada, H., Newnham, J., Hutten, M., Kramer, B. W., Zimmermann, L. J., & Wolfs, T. (2021). Intestinal Goblet Cell Loss during Chorioamnionitis in Fetal Lambs: Mechanistic Insights and Postnatal Implications. Int J Mol Sci, 22(4), 1946. doi:10.3390/ijms22041946

136

Heij, L. R., Tan, X., Kather, J. N., Niehues, J. M., Sivakumar, S., Heussen, N., van der Kroft, G., Damink, S., Lang, S., Aberle, M. R., Luedde, T., Gaisa, N. T., Bednarsch, J., Liu, D. H. W., Cleutjens, J. P. M., Modest, D. P., Neumann, U. P., & Wiltberger, G. J. (2021). Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer. J Clin Med, 10(3), 490. doi:10.3390/jcm10030490

135

Widowski, H., Ophelders, D., van Leeuwen, A., Nikkels, P. G. J., Severens-Rijvers, C. A. H., LaPointe, V. L. S., Cleutjens, J. P. M., Hutten, M. C., Kemp, M. W., Payne, M. S., Saito, M., Usuda, H., Newnham, J. P., Jobe, A. H., Kramer, B. W., Delhaas, T., Wolfs, T., & Reynaert, N. L. (2021). Chorioamnionitis induces changes in ovine pulmonary endogenous epithelial stem/progenitor cells in utero. Pediatr Res, 90(3), 549-558. doi:10.1038/s41390-020-01204-9

134

Bijnen M, Beelen N, Wetzels S, Gaar JV, Vroomen M, Wijnands E, Scheijen JL, van de Waarenburg MPH, Gijbels MJ, Cleutjens JP, Biessen EAL, Stehouwer CDA, Schalkwijk CG, Wouters K. Rage deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in western type diet-fed ldlr(-/-) mice. Sci Rep. 2018;8:15256

133

Barkhuizen M, van Dijck FJP, Jellema RK, Gussenhoven R, Engelbertink I, van Mechelen R, Cleutjens JPM, Seehase M, Steinbusch HWM, Zimmermann LJ, Gavilanes AWD, Kramer BW. The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb. Pediatr Res. 2018 May 9. doi: 10.1038/pr.2018.42.

132

Koelfat, K. V. K.,Visschers, R. G. J., Hodin, C. M. J.M, de Waart, D. R., van Gemert, W. G., Cleutjens, J. P. M., Gijbels, M. J., Shiri-Sverdlov, R., Mookerjee, R. P., Lenaerts, K., Schaap, F. G., Olde Damink, S.W.M. (2018). FXR agonism protects against liver injury in a rat model of intestinal failure-associated liver disease. J Clin Transl Res 3(3): 318-327

131

van den Hil LCL, Vogels RRM, van Barneveld KWY, Gijbels MJJ, Peutz-Kootstra CJ, Cleutjens JPM,  Schreinemacher MHF, Bouvy ND. Comparability of histological outcomes in rats and humans in a hernia model. J Surg Res. 2018; 229: 271–276

130 

Henatsch D, Alsulami S, Duijvestijn AM, Cleutjens JP, Peutz-Kootstra CJ, Stokroos RJ. Histopathological and Inflammatory Features of Chronically Discharging Open Mastoid Cavities: Secondary Analysis of a Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2018;144(3):211-217. 

 129  

Theodorou K, van der Vorst EPC, Gijbels MJ, Wolfs IMJ, Jeurissen M, Theelen TL, Sluimer JC, Wijnands E, Cleutjens JP, Li Y, Jansen Y, Weber C, Ludwig A, Bentzon JF, Bartsch JW, Biessen EAL and Donners M. Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression. Sci Rep. 2017;7:11670.

 128  

Janneke Kessels, Lotte Voeten, Patty Nelemans, Jack Cleutjens, Lisa Maria Hillen, Klara Mosterd, Nicole W. J. Kelleners-Smeets. Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma. A Randomized Clinical Trial. JAMA Dermatol. 2017;153(10):1061-1063

 127  

Uitterdijk A, Springeling T, Hermans KCM, Merkus D, de Beer VJ, Gorsse-Bakker C, Mokelke E, Daskalopoulos EP, Wielopolski PA, Cleutjens JPM, Blankesteijn WM, Prinzen FW, van der Giessen WJ, van Geuns RM, Duncker DJ.  Intermittent pacing therapy favorably modulates infarct remodeling. Basic Res Cardiol. 2017 May;112(3):28.  

 126

Vink RG, Roumans NJ, Čajlaković M, Cleutjens JP, Boekschoten MV, Fazelzadeh P, Vogel MA, Blaak EE, Mariman EC, van Baak MA, Goossens GH. Diet-induced weight loss decreases adipose tissue oxygen tension with parallel changes in adipose tissue phenotype and insulin sensitivity in overweight humans. Int J Obes (Lond). 2017 41, 722-728

125

van Hoof RH, Vöö SA, Sluimer JC, Wijnen NJ, Hermeling E, Schreuder FH, Truijman MT, Cleutjens JP, Daemen MJ, Daemen JH, van Oostenbrugge RJ, Mess WH, Wildberger JE, Heeneman S, Kooi ME. Vessel wall and adventitial DCE-MRI parameters demonstrate similar correlations with carotid plaque microvasculature on histology. J Magn Reson Imaging. 2017; 46: 1053-1059

124

Swarts DR, Rudelius M, Claessen SM, Cleutjens JP, Seidl S, Volante M, Ramaekers FC, Speel EJ. Limited additive value of the Ki-67 proliferative index on patient survival in World Health Organization-classified pulmonary carcinoids. Histopathology. 2017 Feb;70(3):412-422.

123

Poort LJ, Kiewiet CC, Cleutjens JP, Houben R, Hoebers FJ, Kessler PA. Osseointegration and implant stability of extraoral implants in Göttingen minipigs after irradiation. J Craniomaxillofac Surg. 2016 Nov;44(11):1842-1848.

122

Vöö S, Kwee RM, Sluimer JC, Schreuder FH, Wierts R, Bauwens M, Heeneman S, Cleutjens JP, van Oostenbrugge RJ, Daemen JW, Daemen MJ, Mottaghy FM and Kooi ME. Imaging Intraplaque Inflammation in Carotid Atherosclerosis With 18F-Fluorocholine Positron Emission Tomography-Computed Tomography: Prospective Study on Vulnerable Atheroma With Immunohistochemical Validation. Circ Cardiovasc Imaging. 2016;9.

121

Maessen DE, Brouwers O, Gaens KH, Wouters K, Cleutjens JP, Janssen BJ, Miyata T, Stehouwer CD and Schalkwijk CG. Delayed intervention with pyridoxamine improves metabolic function and prevents adipose tissue inflammation and insulin resistance in high-fat diet-induced obese mice. Diabetes. 2016; 65(4): 956-966.

120

Chatrou ML, Cleutjens JP, van der Vusse GJ, Roijers RB, Mutsaers PH and Schurgers LJ. Intra-Section Analysis of Human Coronary Arteries Reveals a Potential Role for Micro-Calcifications in Macrophage Recruitment in the Early Stage of Atherosclerosis. PLoS One. 2015;10:e0142335.

119

Medina I, Cougoule C, Drechsler M, Bermudez B, Koenen RR, Sluimer J, Wolfs I, Doring Y, Herias V, Gijbels M, Bot I, de Jager S, Weber C, Cleutjens J, van Berkel TJ, Sikkink KJ, Mocsai A, Maridonneau-Parini I, Soehnlein O and Biessen EA. Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility. Circulation. 2015; 132:490-501.

118

Theelen TL, Lappalainen JP, Sluimer JC, Gurzeler E, Cleutjens JP, Gijbels MJ, Biessen EA, Daemen MJ, Alitalo K and Yla-Herttuala S. Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice. Atherosclerosis. 2015;241:297-304.

117

Alexander BE,  Achlatis, Osinga, Geest van der HG, Cleutjens JPM, Schutte B, Goeij de JM. Cell kinetics during regeneration in the sponge Halisarca caerulea: how local is the response to tissue damage? PeerJ. 2015;3:e820.

116

Marsch E, Theelen TL, Demandt JA, Jeurissen M, van Gink M, Verjans R, Janssen A, Cleutjens JP, Meex SJ, Donners MM, Haenen GR, Schalkwijk CG, Dubois LJ, Lambin P, Mallat Z, Gijbels MJ, Heemskerk JW, Fisher EA, Biessen EA, Janssen BJ, Daemen MJ, Sluimer JC. Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis. Arteriosclerosis, thrombosis, and vascular biology. 2014;34:2545-2553

115

Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stoger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Targeting macrophage histone deacetylase 3 stabilizes atherosclerotic lesions. EMBO molecular medicine. 2014;6:1124-1132

114

Hanssen NM, Brouwers O, Gijbels MJ, Wouters K, Wijnands E, Cleutjens JP, De Mey JG, Miyata T, Biessen EA, Stehouwer CD, Schalkwijk CG. Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in apoe-/- mice with or without diabetes. Cardiovascular research. 2014;104:160-170

113

Eurlings IM, Dentener MA, Cleutjens JP, Peutz CJ, Rohde GG, Wouters EF, Reynaert NL. Similar matrix alterations in alveolar and small airway walls of copd patients. BMC pulmonary medicine. 2014;14:90

112

Burgmaier M, Schutters K, Willems B, van der Vorst EP, Kusters D, Chatrou M, Norling L, Biessen EA, Cleutjens J, Perretti M, Schurgers LJ, Reutelingsperger CP. Anxa5 reduces plaque inflammation of advanced atherosclerotic lesions in apoe(-/-) mice. Journal of cellular and molecular medicine. 2014;18:2117-2124

111

Alexander BE, Liebrand K, Osinga R, van der Geest HG, Admiraal W, Cleutjens JP, Schutte B, Verheyen F, Ribes M, van Loon E, de Goeij JM. Cell turnover and detritus production in marine sponges from tropical and temperate benthic ecosystems. PloS one. 2014;9:e109486

110

Theys J, Yahyanejad S, Habets R, Span P, Dubois L, Paesmans K, Kattenbeld B, Cleutjens J, Groot AJ, Schuurbiers OC, Lambin P, Bussink J, Vooijs M. High notch activity induces radiation resistance in non small cell lung cancer. Radiotherapy and oncology: journal of the European Society for Therapeutic Radiology and Oncology. 2013;108:440-445

109

Jetten N, Donners MM, Wagenaar A, Cleutjens JP, van Rooijen N, de Winther MP, Post MJ. Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model. PloS one. 2013;8:e68811

108

Jellema RK, Lima Passos V, Zwanenburg A, Ophelders DR, De Munter S, Vanderlocht J, Germeraad WT, Kuypers E, Collins JJ, Cleutjens JP, Jennekens W, Gavilanes AW, Seehase M, Vles HJ, Steinbusch H, Andriessen P, Wolfs TG, Kramer BW. Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep. Journal of neuroinflammation. 2013;10:13

107

Eskens BJ, Mooij HL, Cleutjens JP, Roos JM, Cobelens JE, Vink H, Vanteeffelen JW. Rapid insulin-mediated increase in microvascular glycocalyx accessibility in skeletal muscle may contribute to insulin-mediated glucose disposal in rats. PloS one. 2013;8:e55399

106

Gaens ME, Backes WH, Rozel S, Lipperts M, Sanders SN, Jaspers K, Cleutjens JP, Sluimer JC, Heeneman S, Daemen MJ, Welten RJ, Daemen JW, Wildberger JE, Kwee RM, Kooi ME. Dynamic contrast-enhanced mr imaging of carotid atherosclerotic plaque: Model selection, reproducibility, and validation. Radiology. 2013;266:271-279

105

Hoving S, Heeneman S, Gijbels MJ, Te Poele JA, Visser N, Cleutjens J, Russell NS, Daemen MJ, Stewart FA. Irradiation induces different inflammatory and thrombotic responses in carotid arteries of wildtype c57bl/6j and atherosclerosis-prone apoe(-/-) mice. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2012;105:365-370

104

Goossens GH, Moors CC, van der Zijl NJ, Venteclef N, Alili R, Jocken JW, Essers Y, Cleutjens JP, Clement K, Diamant M, Blaak EE. Valsartan improves adipose tissue function in humans with impaired glucose metabolism: A randomized placebo-controlled double-blind trial. PloS one. 2012;7:e39930

103

Collins JJ, Kuypers E, Nitsos I, Jane Pillow J, Polglase GR, Kemp MW, Newnham JP, Cleutjens JP, Frints SG, Kallapur SG, Jobe AH, Kramer BW. Lps-induced chorioamnionitis and antenatal corticosteroids modulate shh signaling in the ovine fetal lung. American journal of physiology. Lung cellular and molecular physiology. 2012;303:L778-787

102

Austen S, Punt IM, Cleutjens JP, Willems PC, Kurtz SM, Macdonald DW, van Rhijn LW, van Ooij A. (2012) Clinical, radiological, histological and retrieval findings of activ-l and mobidisc total disc replacements: A study of two patients. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 21 Suppl 4:513-520

101

Lobbes MB, Cleutjens JP, Lima Passos V, Frotscher C, Lahaye MJ, Keymeulen KB, Beets-Tan RG, Wildberger J, Boetes C. Density is in the eye of the beholder: Visual versus semi-automated assessment of breast density on standard mammograms. Insights into imaging. 2012;3:91-99

100

Punt IM, Austen S, Cleutjens JP, Kurtz SM, ten Broeke RH, van Rhijn LW, Willems PC, van Ooij A. (2012) Are periprosthetic tissue reactions observed after revision of total disc replacement comparable to the reactions observed after total hip or knee revision surgery? Spine  37:150-159

99

Goossens, G. H., Bizzarri, A., Venteclef, N., Essers, Y., Cleutjens, J. P., Konings, E., Jocken, J. W., Cajlakovic, M., Ribitsch, V., Clement, K., and Blaak, E. E. (2011) Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation. Circulation 124, 67-76

98

van Almen GC, Swinnen M, Carai P, Verhesen W, Cleutjens JP, D'Hooge J, Verheyen FK, Pinto YM, Schroen B, Carmeliet P, Heymans S. (2011) Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. J of Mol Cell Cardiol . 51:318-328

97

Steegh, F. M., Gelens, M. A., Nieman, F. H., van Hooff, J. P., Cleutjens, J. P., van Suylen, R. J., Daemen, M. J., van Heurn, E. L., Christiaans, M. H., and Peutz-Kootstra, C. J. (2011) Early loss of peritubular capillaries after kidney transplantation. J Am Soc Nephrol  22, 1024-1029

96

Roijers, R. B., Debernardi, N., Cleutjens, J. P., Schurgers, L. J., Mutsaers, P. H., and van der Vusse, G. J. (2011) Microcalcifications in early intimal lesions of atherosclerotic human coronary arteries. Am J Pathol  178, 2879-2887

95

van Almen GC, Verhesen W, van Leeuwen RE, van de Vrie M, Eurlings C, Schellings MW, Swinnen M, Cleutjens JP, van Zandvoort MA, Heymans S, Schroen B. (2011) Microrna-18 and microrna-19 regulate ctgf and tsp-1 expression in age-related heart failure. Aging cell 10:769-779

94

Poggi M, Engel D, Christ A, Beckers L, Wijnands E, Boon L, Driessen A, Cleutjens J, Weber C, Gerdes N, Lutgens E. (2011) Cd40l deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice. Arteriosclerosis, thrombosis, and vascular biology . 31:2251-2260

93

Babiker FA, Lorenzen-Schmidt I, Mokelke E, Vanagt WY, Delhaas T, Waltenberger J, Cleutjens JP, Prinzen FW. Long-term protection and mechanism of pacing-induced postconditioning in the heart. Basic Res Cardiol.  2010 Jul;105(4):523-33.

92

Daniels A, van Bilsen M, Janssen BJ, Brouns AE, Cleutjens JP, Roemen TH, Schaart G, van der Velden J, van der Vusse GJ, van Nieuwenhoven FA. Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling.  Acta Physiol (Oxf). 2010 Feb 17.  

91

Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J Exp Med.  2010 Feb;207(2):391-404.

90

Bracke KR, Dentener MA, Papakonstantinou E, Vernooy JH, Demoor T, Pauwels NS, Cleutjens J, van Suylen R, Joos GF, Brusselle GG, Wouters EF. Enhanced Deposition of Low Weight Hyaluronan in Lungs of Cigarette Smoke-Exposed Mice. Am J Respir Cell Mol Biol. . 2010 Jun:42(6):753-761

89

De Goeij JM, De Kluijver A, Van Duyl FC, Vacelet J, Wijffels RH, De Goeij AF, Cleutjens JP, Schutte B. Cell kinetics of the marine sponge Halisarca caerulea reveal rapid cell turnover and shedding. J Exp Biol.  2009 Dec;212(Pt 23):3892-900. 

88

Debats IB, Wolfs TG, Gotoh T, Cleutjens JP, Peutz-Kootstra CJ, van der Hulst RR. Role of arginine in superficial wound healing in man. Nitric Oxide. 2009 Jul 26;21:175-183.

87

Delnoij T, van Suylen RJ, Cleutjens JP, Schalla S, Bekkers SC. In vivo histology by cardiovascular magnetic resonance imaging. Eur Heart J. 2009 Oct:30(20): 2492

86

Russell NS, Hoving S, Heeneman S, Hage JJ, Woerdeman LA, de Bree R, Lohuis PJ, Smeele L, Cleutjens J, Valenkamp A, Dorresteijn LD, Dalesio O, Daemen MJ, Stewart FA. Novel insights into pathological changes in muscular arteries of radiotherapy patients. Radiother Oncol. 2009 Jun 19;92(3):477-483.

85

van den Borne SW, van de Schans VA, Strzelecka AE, Vervoort-Peters HT, Lijnen PM, Cleutjens JP, Smits JF, Daemen MJ, Janssen BJ, Blankesteijn WM. Mouse strain determines the outcome of wound healing after myocardial infarction. Cardiovasc Res. 2009 Nov 1;84(2):273-82.

84

Debats IB, Booi DI, Wehrens KM, Cleutjens J, Deutz NE, van de Hogen E, Bemelmans M, van der Hulst RR. Oral Arginine Supplementation and the Effect on Skin Graft Donor Sites: A Randomized Clinical Pilot Study. J Burn Care Res. 2009 May-Jun;30(3):417-26.

83

Punt IM, Cleutjens JP, de Bruin T, Willems PC, Kurtz SM, van Rhijn LW, Schurink GW, van Ooij A. Periprosthetic tissue reactions observed at revision of total intervertebral disc arthroplasty. Biomaterials. 2009 Apr;30(11):2079-84.

82

Schellings MW, Vanhoutte D, Swinnen M, Cleutjens JP, Debets J, van Leeuwen RE, d'Hooge J, Van de Werf F, Carmeliet P, Pinto YM, Sage EH, Heymans S. Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. J Exp Med. 2009 Jan 16;206(1):113-23.

81

van den Borne SW, Cleutjens JP, Hanemaaijer R, Creemers EE, Smits JF, Daemen MJ, Blankesteijn WM. Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction. Cardiovasc Pathol. 2009 Jan-Feb;18(1):37-43.

80

Sluimer J, Gasc J, Hamming I, van Goor H, Michaud A, van den Akker L, Jütten B, Cleutjens J, Bijnens A, Corvol P, Daemen M, Heeneman S. Angiotensin-converting enzyme 2 (ACE2) expression and activity in human carotid atherosclerotic lesions. J Pathol. 2008 Apr 14;215(3):273-279.

79

Sluimer JC, Gasc JM, van Wanroij JL, Kisters N, Groeneweg M, Sollewijn Gelpke MD, Cleutjens JP, van den Akker LH, Corvol P, Wouters BG, Daemen MJ, Bijnens AP. Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis. J Am Coll Cardiol. Apr 1 2008;51(13):1258-1265.

78

Donners MM, Beckers L, Lievens D, Munnix I, Heemskerk J, Janssen BJ, Wijnands E, Cleutjens J, Zernecke A, Weber C, Ahonen CL, Benbow U, Newby AC, Noelle RJ, Daemen MJ, Lutgens E. The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling. Blood. May 1 2008; 111(9):4596-604.

77

Smeets PJ, Teunissen BE, Willemsen PH, van Nieuwenhoven FA, Brouns AE, Janssen BJ, Cleutjens JP, Staels B, van der Vusse GJ, van Bilsen M. Cardiac hypertrophy is enhanced in PPAR alpha-/- mice in response to chronic pressure overload. Eur Soc Cardiol.  Apr 1 2008;78(1):79-89.

76

Roijers RB, Dutta RK, Cleutjens JP, Mutsaers PH, de Goeij JJ, van der Vusse GJ. Early calcifications in human coronary arteries as determined with a proton microprobe. Anal Chem. Jan 1 2008;80(1):55-61.

75

Megens RT, Oude Egbrink MG, Cleutjens JP, Kuijpers MJ, Schiffers PH, Merkx M, Slaaf DW, van Zandvoort MA. Imaging collagen in intact viable healthy and atherosclerotic arteries using fluorescently labeled CNA35 and two-photon laser scanning microscopy. Molecular Imaging. 2007 Jul-Aug;6(4):247-60.

74

Bruggink AH, van Oosterhout MF, de Jonge N, Cleutjens JP, van Wichen DF, van Kuik J, Tilanus MG, Gmelig-Meyling FH, van den Tweel JG, de Weger RA. Type IV collagen degradation in the myocardial basement membrane after unloading of the failing heart by a left ventricular assist device. Lab Invest. 2007 Nov; 87(11):1125-37.

73

Cheng YY, Pels E, Cleutjens JP, van Suylen RJ, Hendrikse F, Nuijts RM. Corneal Endothelial Viability After Femtosecond Laser Preparation of Posterior Lamellar Discs for Descemet-Stripping Endothelial Keratoplasty. Cornea. Oct 2007;26(9):1118-1122.

72

Driesen RB, Verheyen FK, Dijkstra P, Thone F, Cleutjens JP, Lenders MH, Ramaekers FC, Borgers M. Structural remodelling of cardiomyocytes in the border zone of infarcted rabbit heart. Mol Cell Biochem. 2007 Aug; 302(1-2):225-32.

71

Lerut E, Kuypers DR, Verbeken E, Cleutjens J, Vlaminck H, Vanrenterghem Y, Van Damme B. Acute rejection in non-compliant renal allograft recipients: a distinct morphology. Clin Transplant. May-Jun 2007;21(3):344-351.

70

Vanagt WY, Cornelussen RN, Poulina QP, Blaauw E, Vernooy K, Cleutjens JP, van Bilsen M, Delhaas T, Prinzen FW. Pacing-induced dys-synchrony preconditions rabbit myocardium against ischemia/reperfusion injury. Circulation. Jul 4 2006;114(1 Suppl):I264-269.

69

Bruggink AH, van Oosterhout MF, de Jonge N, Ivangh B, van Kuik J, Voorbij RH, Cleutjens JP, Gmelig-Meyling FH, de Weger RA. Reverse remodeling of the myocardial extracellular matrix after prolonged left ventricular assist device support follows a biphasic pattern. J Heart Lung Transplant. Sep 2006;25(9):1091-1098.

68

Buehler A, van Zandvoort MA, Stelt BJ, Hackeng TM, Schrans-Stassen BH, Bennaghmouch A, Hofstra L, Cleutjens JP, Duijvestijn A, Smeets MB, de Kleijn DP, Post MJ, de Muinck ED. cNGR: a novel homing sequence for CD13/APN targeted molecular imaging of murine cardiac angiogenesis in vivo. Arterioscler Thromb Vasc Biol. Dec 2006;26(12):2681-2687.

67

Schurgers LJ, Teunissen KJ, Knapen MH, Kwaijtaal M, van Diest R, Appels A, Reutelingsperger CP, Cleutjens JP, Vermeer C. Novel conformation-specific antibodies against matrix gamma-carboxyglutamic acid (Gla) protein: undercarboxylated matrix Gla protein as marker for vascular calcification. Arterioscler Thromb Vasc Biol. Aug 2005;25(8):1629-1633.

66

Kolbach DN, Hamulyak K, Prins MH, Neumann HA, Cleutjens JP. Severity of venous insufficiency is related to the density of microvascular deposition of PAI-1, uPA and von Willebrand factor. Vasa. Feb 2004;33(1):19-24.

65

Xia QG, Reinecke A, Dorenkamp M, Storz C, Bitterling H, Penz S, Cleutjens J, Daemen MJ, Simon R, Unger T. Comparison of cardioprotective effects of mibefradil and ramipril in stroke-prone spontaneously hypertensive rats. Acta Pharmacol Sin. Jun 2004;25(6):763-768.

64

De Celle T, Cleutjens JP, Blankesteijn WM, Debets JJ, Smits JF, Janssen BJ. Long-term structural and functional consequences of cardiac ischaemia-reperfusion injury in vivo in mice. Exp Physiol. Sep 2004;89(5):605-615.

63

Schroen B, Heymans S, Sharma U, Blankesteijn WM, Pokharel S, Cleutjens JP, Porter JG, Evelo CT, Duisters R, van Leeuwen RE, Janssen BJ, Debets JJ, Smits JF, Daemen MJ, Crijns HJ, Bornstein P, Pinto YM. Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy. Circ Res. Sep 3 2004;95(5):515-522.

62

Lutgens LC, Deutz N, Granzier-Peeters M, Beets-Tan R, De Ruysscher D, Gueulette J, Cleutjens J, Berger M, Wouters B, von Meyenfeldt M, Lambin P. Plasma citrulline concentration: a surrogate end point for radiation-induced mucosal atrophy of the small bowel. A feasibility study in 23 patients. J Radiat Oncol Biol Phys. Sep 1 2004;60(1):275-285.

61

Kornet L, Bergen AA, Hoeks AP, Cleutjens JP, Oostra RJ, Daemen MJ, van Soest S, Reneman RS. In patients with pseudoxanthoma elasticum a thicker and more elastic carotid artery is associated with elastin fragmentation and proteoglycans accumulation. Ultrasound Med Biol. Aug 2004;30(8):1041-1048.

60

Pokharel S, van Geel PP, Sharma UC, Cleutjens JP, Bohnemeier H, Tian XL, Schunkert H, Crijns HJ, Paul M, Pinto YM. Increased myocardial collagen content in transgenic rats overexpressing cardiac angiotensin-converting enzyme is related to enhanced breakdown of N-acetyl-Ser-Asp-Lys-Pro and increased phosphorylation of Smad2/3. Circulation. Nov 9 2004;110(19):3129-3135.

59

Sharma UC, Pokharel S, van Brakel TJ, van Berlo JH, Cleutjens JP, Schroen B, Andre S, Crijns HJ, Gabius HJ, Maessen J, Pinto YM. Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. Nov 9 2004;110(19):3121-3128.

58

Creemers EE, Davis JN, Parkhurst AM, Leenders P, Dowdy KB, Hapke E, Hauet AM, Escobar PG, Cleutjens JP, Smits JF, Daemen MJ, Zile MR, Spinale FG. Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice. Am J Physiol Heart Circ Physiol. Jan 2003;284(1):H364-371. 

57

Heeneman S, Cleutjens JP, Faber BC, Creemers EE, van Suylen RJ, Lutgens E, Cleutjens KB, Daemen MJ. The dynamic extracellular matrix: intervention strategies during heart failure and atherosclerosis. J Pathol. Jul 2003;200(4):516-525.

56

Lutgens LC, Deutz NE, Gueulette J, Cleutjens JP, Berger MP, Wouters BG, von Meyenfeldt MF, Lambin P. Citrulline: a physiologic marker enabling quantitation and monitoring of epithelial radiation-induced small bowel damage. Int J Radiat Oncol Biol Phys. Nov 15 2003;57(4):1067-1074.

55

Ratajska A, Cleutjens JP. Embryogenesis of the rat heart: the expression of collagenases. Basic Res Cardiol. May 2002;97(3):189-197.

54

Lardenoye JH, de Vries MR, Lowik CW, Xu Q, Dhore CR, Cleutjens JP, van Hinsbergh VW, van Bockel JH, Quax PH. Accelerated atherosclerosis and calcification in vein grafts: a study in APOE*3 Leiden transgenic mice. Circ Res. Oct 4 2002;91(7):577-584.

53

Cleutjens JP, Creemers EE. Integration of concepts: cardiac extracellular matrix remodeling after myocardial infarction. J Card Fail.  Dec 2002;8(6 Suppl):S344-348.

52

Sandmann S, Claas R, Cleutjens JP, Daemen MJ, Unger T. Calcium channel blockade limits cardiac remodeling and improves cardiac function in myocardial infarction-induced heart failure in rats. J Cardiovasc Pharmacol. Jan 2001;37(1):64-77.

51

van Gijn ME, Snel F, Cleutjens JP, Smits JF, Blankesteijn WM. Overexpression of components of the Frizzled-Dishevelled cascade results in apoptotic cell death, mediated by beta-catenin. Exp Cell Res. Apr 15 2001;265(1):46-53.

50

Schurgers LJ, Dissel PE, Spronk HM, Soute BA, Dhore CR, Cleutjens JP, Vermeer C. Role of vitamin K and vitamin K-dependent proteins in vascular calcification. Z Kardiol. 2001;90 Suppl 3:57-63.

49

Creemers EE, Cleutjens JP, Smits JF, Daemen MJ. Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure? Circ Res. Aug 3 2001;89(3):201-210.

48

van Eickels M, Grohe C, Cleutjens JP, Janssen BJ, Wellens HJ, Doevendans PA. 17beta-estradiol attenuates the development of pressure-overload hypertrophy. Circulation. Sep 18 2001;104(12):1419-1423.

47

Blankesteijn WM, Creemers E, Lutgens E, Cleutjens JP, Daemen MJ, Smits JF. Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice. Acta Physiol Scand. Sep 2001;173(1):75-82.

46

Spronk HM, Soute BA, Schurgers LJ, Cleutjens JP, Thijssen HH, De Mey JG, Vermeer C. Matrix Gla protein accumulates at the border of regions of calcification and normal tissue in the media of the arterial vessel wall. Biochem Biophys Res Commun. Nov 30 2001;289(2):485-490.

45

Dhore CR, Cleutjens JP, Lutgens E, Cleutjens KB, Geusens PP, Kitslaar PJ, Tordoir JH, Spronk HM, Vermeer C, Daemen MJ. Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arterioscler Thromb Vasc Biol. Dec 2001;21(12):1998-2003.

44

Creemers E, Cleutjens J, Smits J, Heymans S, Moons L, Collen D, Daemen M, Carmeliet P. Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction. Am J Pathol. Jun 2000;156(6):1865-1873.

43

Heymans S, Luttun A, Nuyens D, Theilmeier G, Creemers E, Moons L, Dyspersin GD, Cleutjens JP, Shipley M, Angellilo A, Levi M, Nube O, Baker A, Keshet E, Lupu F, Herbert JM, Smits JF, Shapiro SD, Baes M, Borgers M, Collen D, Daemen MJ, Carmeliet P. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nat Med. Oct 1999;5(10):1135-1142.

42

Cleutjens JP, Blankesteijn WM, Daemen MJ, Smits JF. The infarcted myocardium: simply dead tissue, or a lively target for therapeutic interventions. Cardiovasc Res. Nov 1999;44(2):232-241.

41

van Oosterhout MF, Prinzen FW, Arts T, Schreuder JJ, Vanagt WY, Cleutjens JP, Reneman RS. Asynchronous electrical activation induces asymmetrical hypertrophy of the left ventricular wall. Circulation. Aug 11 1998;98(6):588-595.

40

Vos MA, de Groot SH, Verduyn SC, van der Zande J, Leunissen HD, Cleutjens JP, van Bilsen M, Daemen MJ, Schreuder JJ, Allessie MA, Wellens HJ. Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling. Circulation. Sep 15 1998;98(11):1125-1135.

39

Weber KT, Sun Y, Katwa LC, Cleutjens JP. Tissue repair and angiotensin II generated at sites of healing. Basic Res Cardiol. Apr 1997;92(2):75-78.

38

de Vries JE, Vork MM, Roemen TH, de Jong YF, Cleutjens J  P, van der Vusse GJ, van Bilsen M. Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes. J Lipid Res. Jul 1997;38(7):1384-1394.

37

Ulrich MM, Janssen AM, Daemen MJ, Rappaport L, Samuel JL, Contard F, Smits JF, Cleutjens JP. Increased expression of fibronectin isoforms after myocardial infarction in rats. J Mol Cell Cardiol. Sep 1997;29(9):2533-2543.

36

Weber KT, Sun Y, Cleutjens JP. Structural remodeling of the infarcted rat heart. Exs. 1996;76:489-499.

35

Tyagi SC, Cleutjens JP. Myocardial collagenase: purification and structural characterization. Can J Cardiol. Feb 1996;12(2):165-171.

34

Cleutjens JP. The role of matrix metalloproteinases in heart disease. Cardiovasc Res. Nov 1996;32(5):816-821.

33

Weber KT, Sun Y, Katwa LC, Cleutjens JP. Connective tissue; a metabolic entity? J Mol Cell Cardiol. Jan 1995;27(1):107-120.

32

Weber KT, Sun Y, Cleutjens JPM. Structural remodeling of the myocardium postinfarction: potential mechanisms and influence of therapy. Cardiology in Review 1995; 3:53-65.

31

Katwa LC, Ratajska A, Cleutjens JP, Sun Y, Zhou G, Lee SJ, Weber KT. Angiotensin converting enzyme and kininase-II-like activities in cultured valvular interstitial cells of the rat heart. Cardiovasc Res. Jan 1995;29(1):57-64.

30

Weber KT, Sun Y, Katwa LC, Cleutjens JP, Zhou G. Connective tissue and repair in the heart. Potential regulatory mechnisms. Ann N Y Acad Sci. Mar 27 1995;752:286-299.

29

Weber KT, Sun Y, Guarda E, Katwa LC, Ratajska A, Cleutjens JP, Zhou G. Myocardial fibrosis in hypertensive heart disease: an overview of potential regulatory mechanisms. Eur Heart J. May 1995;16 Suppl C:24-28.

28

Cleutjens JP, Kandala JC, Guarda E, Guntaka RV, Weber KT. Regulation of collagen degradation in the rat myocadium after infarction. J Mol Cell Cardiol. Jun 1995;27(6):1281-1292.

27

Ausma J, Cleutjens J, Thone F, Flameng W, Ramaekers F, Borgers M. Chronic hibernating myocardium: interstitial changes. Mol Cell Biochem. Jun 7-21 1995;147(1-2):35-42.

26

Cleutjens JP, Verluyten MJ, Smiths JF, Daemen MJ. Collagen remodeling after myocardial infarction in the rat heart. Am J Pathol. Aug 1995;147(2):325-338.

25

Smits JF, Passier RC, Nelissen-Vrancken HJ, Cleutjens JP, Kuizinga MC, Daemen MJ. Does ACE inhibition limit structural changes in the heart following myocardial infarction? Eur Heart J. Dec 1995;16 Suppl N:46-51.

24

Weber KT, Sun Y, Tyagi SC, Cleutjens JP. Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms. J Mol Cell Cardiol. Mar 1994;26(3):279-292.

23

Ratajska A, Campbell SE, Cleutjens JP, Weber KT. Angiotensin II and structural remodeling of coronary vessels in rats. J Lab Clin Med. Sep 1994;124(3):408-415.

22

Sun Y, Cleutjens JP, Diaz-Arias AA, Weber KT. Cardiac angiotensin converting enzyme and myocardial fibrosis in the rat. Cardiovasc Res. Sep 1994;28(9):1423-1432.

21

Volders PG, Willems IE, Cleutjens JP, Arends JW, Havenith MG, Daemen MJ. Interstitial collagen is increased in the non-infarcted human myocardium after myocardial infarction. J Mol Cell Cardiol.  Nov 1993;25(11):1317-1323.

20

Smits JF, van Krimpen C, Schoemaker RG, Cleutjens JP, Daemen MJ. Angiotensin II receptor blockade after myocardial infarction inrats: effects on hemodynamics, myocardial DNA synthesis, and interstitial collagen content.  J. Cardiovasc Pharmacol. 1992;20(5):772-778.

19

Bosman FT, Havenith MG, Visser R, Cleutjens JP. Basement membranes in neoplasia. Prog Histochem Cytochem. 1992;24(4):1-92.

18

van Kleef EM, Smits JF, De Mey JG, Cleutjens JP, Lombardi DM, Schwartz SM, Daemen MJ. Alpha 1-adrenoreceptor blockade reduces the angiotensin II-induced vascualr smooth muscle cell DNA synthesis in the rat thoracic aorta and carotid artery. Circ Res. Jun 1992;70(6):1122-1127.

17

van Baar HM, Perret CM, van Vlijmen-Willems IM, Cleutjens JP, Mackie EJ, Happle R, Schalkwijk J. Expression of tenascin in perifollicular connective tissue: comparison of normal scalp and alopercia areata. Arch Dermatol Res. 1991;283(2):86-90.

16

Smits JF, Cleutjens JP, van Krimpen C, Schoemaker RG, Daemen MJ. Cardiac remodeling in hypertension and following myocardial infarction: effects of arteriolar vasadilators. Basic Res Cardiol. 1991;86 Suppl 1:133-139. 

15

van Krimpen C, Schoemaker RG, Cleutjens JP, Smits JF, Struyker-Boudier HA, Bosman FT, Daemen MJ. Angiotensin I converting enzyme inhibitors and cardiac remodeling. Basic Res Cardiol. 1991;86 Suppl 1:149-155.

14

van Krimpen C, Smits JF, Cleutjens JP, Debets JJ, Schoemaker RG, Struyker Boudier HA, Bosman FT, Daemen MJ. DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: effect of captopril. J Mol Cell Cardiol. Nov 1991;23(11):1245-1253.

13

Havenith MG, Dingemans KP, Cleutjens JP, Wagenaar SS, Bosman FT. Basement membranes in bronchogenic squamous cell carcinoma: an immunohistochemical and ultrastructural study. Ultrastruct Pathol. Jan-Feb 1990;14(1):51-63.

12

Cleutjens JP, Havenith MG, Beek C, Vallinga M, Ten Kate J, Bosman FT. Origin of basement membrane type IV collagen in xenografted human epithelial tumor cell lines.  Am J Pathol. May 1990;136(5):1165-1172.

11

Cleutjens JP, Havenith MG, Kasper M, Vallinga M, Bosman FT. Absence of type IV collagen in the centre of the corneal epithelial basement membrane. Histochem J. Dec 1990;22(12):688-694.

10

Cleutjens JPM. Basement membrane heterogeneity: University of Limburg, Maastricht, The Netherlands, 1989:131.

9

Cleutjens JP, Havenith M, Beek C, Vallinga M, Bosman FT. Basement membrane heterogeneity detected by monoclonal antibodies. Acta Histochem Suppl. 1989;37:179-184.

8

Cleutjens JP, Havenith MG, Vallinga M, Beek C, Bosman FT. Monoclonal antibodies to native basement membranes reveal heterogeneous immunoreactivity patterns. Histochemistry. 1989;92(5):407-412.

7

Havenith MG, van Zandvoort EH, Cleutjens JP, Bosman FT. Basement membrane deposition in benign and maligmant naevo-melanocytic lesions: an immunohistochemical study with antibodies to type IV collagen and laminin. Histopathology. Aug 1989;15(2):137-146.

6

Cleutjens J, Havenith MG, Beek C, Vallinga M, Bosman FT. Basale-membraan heterogeniteit vastgesteld met behulp van monoklonale antilichamen. Nederlands Tijdschrift voor Geneeskunde.  1988; 132:46-47.

5

Bosman FT, Cleutjens J, Beek C, Havenith M. Basement membrane heterogeneity. Histochem J. Nov 1989;21(11):629-633.

4

Havenith MG, Cleutjens JP, Beek C, vd Linden E, De Goeij AF, Bosman FT. Human specific anti-type IV collagen monoclonal antibodies, characterization and immunohistochemical application. Histochemistry. 1987;87(2):123-128.

3

Cleutjens J, Havenith M, Beek C, Ummelen M, Bosman FT. Basement membrane heterogeneity detected by monoclonal antibodies against human amnion. Journal of Histochemistry and Cytochemistry 1987; 35:1017.

2

Visser R, van der Beek JM, Havenith MG, Cleutjens JP, Bosman FT. Immunocytochemical detection of basement membrane antigens in the histopathological evaluation of laryngeal dysplasia and neoplasia. Histopathology. Feb 1986;10(2):171-180.

1

Bosman FT, Havenith M, Cleutjens JP. Basement membranes in cancer. Ultrastruct Pathol. 1985;8(4):291-304.